In vitro data were discovered that characterize cytochrome P-450 (CYP-450) enzymes as prospective sizeable contributors to the principal metabolism of a number of exogenous cannabinoids, and scientific pharmacogenetic info further more aid CYP2C9 as a substantial contributor to THC metabolism, and also a pharmacokinetic conversation examine using k

Twelve metabolites of the synthetic cannabinoid, EAM-2201, ended up tentatively recognized in human hepatocytes in vitro, and in human liver and urine specimens in vivo for The 1st time. The computed details are in comparison with the readily available initial theory calculations and experimental data, showing higher accuracy of your 2NN-MEAM in